A fasting-mimicking diet combined with chemotherapy resulted in a 300-400% increase in the chance of killing 90-100% of cancer cells in women with breast cancer.
DNA damage in normal T-cells was less in patients who received the fasting-mimicking diet with chemotherapy compared to chemotherapy alone.
The fasting-mimicking diet holds great promise as a complementary therapy for cancer because, when coupled with chemotherapy, the diet induces differential stress resistance – a phenomenon in which normal cells are protected from stress, but damaged cells are not.
Fasting creates a hostile microenvironment for cancer cells, sensitizing them to chemotherapy drugs, and promoting cell death. This exploits the inability of cancer cells to adapt to extreme environments.